Eliezer Masliah Selected Research

Tauopathies

1/2021	Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2.
1/2021	Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
11/2018	SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
1/2018	Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau.
1/2018	Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders.
10/2017	Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.
11/2015	Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies.
12/2014	Primary age-related tauopathy (PART): a common pathology associated with human aging.
9/2012	Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.
8/2011	Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease.

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Eliezer Masliah Research Topics

Disease

173	Parkinson Disease (Parkinson's Disease) 01/2024 - 03/2002
162	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 02/2001
100	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 02/2001
97	Dementia (Dementias) 10/2023 - 05/2002
65	Synucleinopathies 01/2023 - 02/2002
34	Multiple System Atrophy 01/2023 - 06/2002
32	Cognitive Dysfunction 11/2023 - 10/2002
27	Lewy Body Disease (Lewy Body Dementia) 01/2024 - 03/2002
26	Amyloid Plaque 10/2020 - 07/2002
25	Neuroinflammatory Diseases 04/2024 - 11/2005
21	Gliosis 04/2024 - 07/2003
21	Inflammation (Inflammations) 05/2022 - 07/2003
21	Neurocognitive Disorders (Clerambault Syndrome) 01/2020 - 04/2006
18	HIV Infections (HIV Infection) 10/2019 - 06/2002
18	Encephalitis (Encephalitis, Rasmussen) 01/2019 - 06/2002
17	Huntington Disease (Huntington's Disease) 11/2018 - 12/2008
15	Parkinsonian Disorders (Parkinsonism) 01/2019 - 06/2003
13	Disease Progression 10/2022 - 09/2002
13	Nervous System Diseases (Neurological Disorders) 01/2021 - 01/2003
13	Tauopathies 01/2021 - 09/2010
12	Infections 01/2017 - 09/2002
10	Mitochondrial Diseases (Mitochondrial Disease) 03/2023 - 01/2003
9	Neuroblastoma 01/2019 - 06/2003
9	Memory Disorders (Memory Loss) 01/2019 - 11/2010
8	Frontotemporal Dementia (Semantic Dementia) 10/2017 - 10/2006
8	Acquired Immunodeficiency Syndrome (AIDS) 02/2008 - 05/2002
6	Neoplasms (Cancer) 10/2023 - 12/2013
6	Atrophy 11/2018 - 03/2009
6	Prion Diseases (Transmissible Spongiform Encephalopathies) 02/2014 - 09/2007
5	Amyloidosis 01/2022 - 03/2003
5	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2018 - 08/2012
4	Chronic Disease (Chronic Diseases) 01/2021 - 03/2009
4	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2017 - 09/2007
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2015 - 10/2006
4	Stroke (Strokes) 10/2012 - 09/2007
4	Scrapie 08/2012 - 06/2005
3	Schizophrenia (Dementia Praecox) 01/2019 - 09/2008
3	Corticobasal Degeneration 01/2018 - 08/2012
3	Demyelinating Diseases (Demyelinating Disease) 01/2018 - 09/2014
3	Proteostasis Deficiencies 01/2016 - 07/2009
3	Ataxia (Dyssynergia) 09/2015 - 11/2005

Drug/Important Bio-Agent (IBA)

127	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2001
112	SynucleinsIBA 04/2024 - 06/2003
90	alpha-SynucleinIBA 01/2024 - 10/2001
85	Amyloid (Amyloid Fibrils)IBA 01/2023 - 02/2001
35	Amyloid beta-PeptidesIBA 10/2023 - 07/2002
31	Peptides (Polypeptides)IBA 01/2024 - 08/2002
17	PrionsIBA 12/2020 - 03/2004
12	CytokinesIBA 04/2024 - 11/2003
12	CalciumIBA 01/2017 - 08/2003
11	polyglutamineIBA 01/2018 - 07/2009
11	cerebrolysinIBA 01/2016 - 05/2006
10	Amyloidogenic ProteinsIBA 01/2022 - 09/2006
10	Phosphotransferases (Kinase)IBA 01/2018 - 09/2002
10	ApolipoproteinsIBA 01/2018 - 02/2002
9	Neuroprotective AgentsIBA 01/2023 - 02/2007
9	AdiponectinIBA 01/2022 - 07/2014
9	Protein AggregatesIBA 12/2021 - 06/2009
9	EnzymesIBA 01/2021 - 09/2007
9	Apolipoproteins E (ApoE)IBA 01/2019 - 12/2002
9	AntibodiesIBA 01/2018 - 09/2010
9	SynaptophysinIBA 01/2017 - 12/2002
8	Biomarkers (Surrogate Marker)IBA 01/2016 - 09/2007
8	beta-SynucleinIBA 05/2009 - 08/2002
7	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021 - 03/2004
7	Apolipoprotein E4IBA 01/2019 - 02/2002
7	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2017 - 03/2009
6	Protein Isoforms (Isoforms)IBA 10/2023 - 10/2001
6	VaccinesIBA 01/2022 - 02/2010
6	RNA (Ribonucleic Acid)IBA 01/2021 - 12/2005
6	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2007
6	tau Proteins (tau Protein)IBA 10/2019 - 01/2011
6	Glial Fibrillary Acidic ProteinIBA 01/2017 - 07/2003
6	Cholinergic Agents (Cholinergics)IBA 10/2015 - 10/2002
5	Small Interfering RNA (siRNA)IBA 01/2024 - 10/2005
5	UbiquitinIBA 01/2021 - 10/2006
5	Prion ProteinsIBA 12/2020 - 06/2005
5	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2020 - 09/2005
5	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2014 - 12/2003
4	Toll-Like Receptor 2IBA 01/2021 - 10/2015
4	Glucosylceramidase (Glucocerebrosidase)IBA 01/2021 - 08/2014
4	InterferonsIBA 10/2020 - 12/2013
4	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020 - 03/2010
4	CaspasesIBA 09/2015 - 12/2003
4	Beclin-1IBA 09/2013 - 06/2008
4	Peptide Hydrolases (Proteases)FDA Link 08/2012 - 06/2005
4	Neprilysin (Neutral Endopeptidase)IBA 01/2011 - 03/2003
4	CholesterolIBA 02/2010 - 08/2006
3	Sunitinib (Sutent)FDA Link 10/2023 - 12/2014
3	AntioxidantsIBA 03/2023 - 07/2006
3	Apolipoproteins B (ApoB)IBA 01/2022 - 01/2015
3	LipidsIBA 09/2019 - 08/2006
3	CalpainIBA 12/2018 - 05/2007
3	MicroRNAs (MicroRNA)IBA 01/2017 - 04/2010
3	Nerve Growth Factor (NGF)IBA 01/2016 - 02/2013
3	Complement System Proteins (Complement)IBA 09/2012 - 08/2002

Therapy/Procedure

43	Therapeutics 01/2022 - 05/2002
22	Immunotherapy 04/2024 - 10/2005
10	Highly Active Antiretroviral Therapy (HAART) 06/2014 - 05/2002
4	Transplantation 06/2020 - 04/2014